ACHIEVEMENTS OF GENETIC ENGINEERING

Uristemova S.T. – students of KSTU( group BT-15-1)
Aibolova G.K. – students of KSTU (group BT-15-1) Supervisor – teacher Igembekova A.Z.

ACHIEVEMENTS OF GENETIC ENGINEERING

Genetic engineering is the alteration of genetic material by direct intervention in genetic processes with the purpose of producing new substances or improving functions of existing organisms. It is a very young, exciting, and controversial branch of the biological sciences. On the one hand, it offers the possibility of cures for diseases and countless material improvements to daily life. Hopes for the benefits of genetic engineering are symbolized by the Human Genome Project, a vast international effort to categorize all the genes in the human species. On the other hand, genetic engineering frightens many with its potential for misuse, either in Nazi-style schemes for population control or through simple bungling that might produce a biological holocaust caused by a man-made virus. Symbolic of the alarming possibilities is the furor inspired by a single concept on the cutting edge of genetic engineering: cloning. Genetic engineering, also called genetic modification, is the direct manipulation of an organism’s genome using biotechnology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism.
Genes may be removed, or «knocked out», using a nuclease.
Genetically modified pig.
The enviropig is the trademark for a genetically modified line of Yorkshire pigs with the capability to digest plant phosphorus more efficiently than ordinary unmodified pigs that was developed at the University of Guelph. Enviropigs produce the enzyme phytase in the salivary glands that is secreted in the saliva. In 2006 the scientists from National Taiwan University’s Department of Animal Science and Technology managed to breed three green-glowing pigs using green fluorescent protein.Fluorescent pigs can be used to study human organ transplants, regenerating ocular photoreceptor cells, neuronal cells in the brain, regenerative medicine via stem cells, tissue engineering, and other diseases. In 2015, researchers at the Beijing Genomics Institute used transcription activatorlike effector nucleases to create a miniature version of the Bama breed of pigs, and offered them for sale to consumers. In 2017 scientists at the Roslin Institute of the University of Edinburgh, reported they had bred pigs with a modified CD163 gene. These pigs were completely resistant to Porcine Reproductive and Respiratory Syndrome, a disease that causes major losses in the world- wide pig industry.

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